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NFIA, or Nuclear Factor I A, is a transcription factor that plays crucial roles in the regulation of gene expression, cellular differentiation, and development. Positioned predominantly within the nucleus of cells, NFIA belongs to the Nuclear Factor I (NFI) family, which consists of highly conserved DNA-binding proteins involved in the transcriptional control of various genes. One of the primary functions of NFIA is its involvement in the regulation of gene expression through binding to specific DNA sequences, known as NFIA recognition elements, within the promoter regions of target genes. By interacting with transcriptional co-regulators and chromatin-modifying enzymes, NFIA can either activate...
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